Large Cities Perfect to Start a Business

Large Cities Perfect to Start a Business

With May 4th kicking off National Small Business Week but many small-business owners still struggling to hire new employees, WalletHub has released its report on 2025’s Best Large Cities to Start a Business. In order to help aspiring entrepreneurs maximize their chances for long-term prosperity, WalletHub compared 100 U.S. cities across 19 key indicators of startup viability. The data set ranges from the five-year business-survival rate to labor costs to office-space affordability.

Best Large Cities to Start a Business

  1. Orlando, FL
  2. Tampa, FL
  3. Austin, TX
  4. Jacksonville, FL
  5. Miami, FL
  6. St. Petersburg, FL
  7. Boise, ID
  8. Atlanta, GA
  9. Raleigh, NC
  10. Hialeah, FL
  11. Fort Worth, TX
  12. Durham, NC
  13. Charlotte, NC
  14. Scottsdale, AZ
  15. Arlington, TX
  16. Dallas, TX
  17. Chandler, AZ
  18. Glendale, AZ
  19. Aurora, CO
  20. Mesa, AZ

Best vs. Worst

  • Toledo, Ohio, has the lowest average annual rent for office space, which is 6.7 times cheaper than in San Francisco, the city with the highest.
  • Cleveland has the lowest labor costs (median annual income), which is 4.5 times lower than in Fremont, California, the city with the highest.
  • Laredo, Texas and Toledo, Ohio, have the lowest cost-of-living index, which is 2.2 times lower than in Honolulu, the city with the highest.
  • Miami and Hialeah, Florida, have the most startups per 100,000 residents, which is 3.2 times more than in Toledo, Ohio, the city with the fewest.